The new Zach Cregger-directed *Resident Evil* reboot opened to a franchise-record $60 million domestically in mid-September before dropping 61% to roughly $23 million in its second frame amid heavy competition from re-releases and new wide entries. Strong critical reception, solid word-of-mouth, and an R-rated horror appeal helped it clear $110 million domestically by early October, yet typical post-horror hold patterns and theater cannibalization point to a further decline for the third weekend. Traders are pricing in modest single-digit drops versus steeper erosion, with key swing factors including daily tracking through the Columbus Day frame and audience retention against fresh titles like *Heart of the Beast*. China and Japan openings arrive shortly after but will not factor into domestic resolution.