Polymarket traders assign a 92.3% implied probability to "No" for a new coronavirus pandemic in 2026, reflecting WHO and CDC surveillance data showing no novel coronaviruses—distinct from SARS-CoV-2—with sustained human-to-human transmission potential. Enhanced global monitoring post-COVID, including genomic sequencing networks, has detected only distant animal reservoirs without spillover threats, while widespread population immunity from prior infections and vaccines curbs sarbecovirus outbreak risks. Epidemiological baselines indicate pandemics require rare zoonotic jumps and high transmissibility, unseen in recent years. Realistic challenges include undetected variants in under-monitored regions or abrupt evolutionary shifts, though current trends favor stability; watch for quarterly WHO epidemiological updates and emerging pathogen reports.