US-Iran negotiations to end the seven-month conflict remain centered on Iran's stockpile of roughly 440 kg of uranium enriched to 60 percent, most of which is believed buried in sealed tunnels at Isfahan and other sites following US-Israeli airstrikes in 2025 and early 2026. Vice President JD Vance stated in early October that Tehran must deliver a meaningful reduction in enrichment capacity to satisfy US demands. Iran has not resumed enrichment or permitted IAEA inspectors back to the damaged facilities, while reports indicate its leadership prefers keeping the material inside the country rather than allowing removal or dilution abroad. Ongoing talks include options for on-site downgrading under international oversight, but no final agreement has been reached and the exact status of surviving stocks remains unverified.