US-Iran negotiations following the 2025-2026 conflict center on the disposition of Iran's remaining stockpile of uranium enriched up to 60%, estimated at over 200 kg in some locations after US-Israeli strikes damaged enrichment facilities. The June 2026 memorandum of understanding provides for down-blending this material on Iranian soil under IAEA supervision as the minimum approach, with details deferred to final-deal talks. US Vice President JD Vance stated in early October that Tehran must deliver a meaningful reduction in enrichment capacity to conclude the seven-month conflict. Iran has resisted shipping stockpiles abroad, and recent reporting indicates no agreement on US acquisition or removal of the material. Ongoing diplomatic discussions, including potential IAEA access and verification, continue to shape prospects for any transfer.